Most extreme reaction to contact with semen

Most women don't mind semen too much, though some unduly fastidious ones complain about its smell or stickiness. Some females, however, have a quite extraordinary reaction to seminal fluid: they are happily rare. In one case reported in 1967 a girl had an acute allergic reaction to human sperm. She came from a family with a long history of various kinds of allergy, including eczema, asthma, and dermatitis. A short time after her first sexual experience she developed a rash and asthma; her lips, eyelids, tongue, and throat became swollen, she had violent pains in the pelvis and finally lost consciousness. Most of these symptoms appeared every time she had sexual intercourse: they began within half an hour and lasted well into the next day. When semen diluted one part per million was injected under her skin it left an angry weal, so intense was the girl's reaction (P. Vaughan "The Pill on Trial").
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