Lorenzo Ghiberti's Adam and Eve in the "Gate's of Paradise" of the Baptistry in Florence.

Credit: Thermos @ Wikipedia Commons

According to one authority (E. Carr, "European Erotic Art"), the first nude of the Renaissance - a nude that is "not unaesthetic and submissive, the usual appearance of the Byzantine and mediaeval Eves" - is Lorenzo Ghiberti's Eve on the eastern door of the Baptistry in Florence, sculptured in relief in 1425.

She is given the Hebrew name of Eve and she is being called into existence by Jehovah, but she has the beautiful expression reminiscent of the Greek Venus on the Ludovisi throne and the body is "unashamedly beautiful..." (Ghiberti also wrote the earliest known autobiography of an artist.)